protac pd-1/pd-l1 degrader-1 — TargetMol Chemicals

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Search Results for " protac pd-1/pd-l1 degrader-1 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T40112	PROTAC PD-1/PD-L1 degrader-1	PROTAC PD-1/PD-L1 degrader-1
	PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride		PD-1/PD-L1
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...		PD-1/PD-L1
T40574	Br-C3-methyl ester	Br-C3-methyl ester
	Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.
T40111	BMS-1166-N-piperidine-CO-N-piperazine
	BMS-1166-N-piperidine-CO-N-piperazine is a chemical compound that contains a PD-1/PD-L1 immune checkpoint ligand and a PROTAC linker. It can be utilized in the synthesis of PROTAC PD-1/PD-L1 degrader-1, which effectivel...
T40110	BMS-1166-N-piperidine-COOH
	BMS-1166-N-piperidine-COOH is a chemical compound that functions as the BMS-1166-based moiety. It binds to the E3 ligase ligand through a linker, leading to the formation of PROTAC PD-1/PD-L1 degrader-1, which facilitate...